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Interleukin-21 Is Required for the Development of Type 1 Diabetes in NOD Mice

OBJECTIVE: Interleukin (IL)-21 is a type 1 cytokine that has been implicated in the pathogenesis of type 1 diabetes via the unique biology of the nonobese diabetic (NOD) mouse strain. The aim of this study was to investigate a causal role for IL-21 in type 1 diabetes. RESEARCH DESIGN AND METHODS: We...

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Detalles Bibliográficos
Autores principales:	Sutherland, Andrew P.R., Van Belle, Tom, Wurster, Andrea L., Suto, Akira, Michaud, Monia, Zhang, Dorothy, Grusby, Michael J., von Herrath, Matthias
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671036/ https://www.ncbi.nlm.nih.gov/pubmed/19208913 http://dx.doi.org/10.2337/db08-0882

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