Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

OBJECTIVE: Results from the Diabetes Control Complications Trial (DCCT) and the subsequent Epidemiology of Diabetes Interventions and Complications (EDIC) Study and more recently from the U.K. Prospective Diabetes Study (UKPDS) have revealed that the deleterious end-organ effects that occurred in bo...

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Detalles Bibliográficos
Autores principales: Brasacchio, Daniella, Okabe, Jun, Tikellis, Christos, Balcerczyk, Aneta, George, Prince, Baker, Emma K., Calkin, Anna C., Brownlee, Michael, Cooper, Mark E., El-Osta, Assam
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671038/
https://www.ncbi.nlm.nih.gov/pubmed/19208907
http://dx.doi.org/10.2337/db08-1666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671038/
https://www.ncbi.nlm.nih.gov/pubmed/19208907
http://dx.doi.org/10.2337/db08-1666

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