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Muscle Microvascular Dysfunction in Central Obesity Is Related to Muscle Insulin Insensitivity but Is Not Reversed by High-Dose Statin Treatment

OBJECTIVE: To test the hypotheses that decreased insulin-mediated glucose disposal in muscle is associated with a reduced muscle microvascular exchange capacity (K(f)) and that 6 months of high-dose statin therapy would improve microvascular function in people with central obesity. RESEARCH DESIGN A...

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Detalles Bibliográficos
Autores principales: Clough, Geraldine F., Turzyniecka, Magdalena, Walter, Lara, Krentz, Andrew J., Wild, Sarah H., Chipperfield, Andrew J., Gamble, John, Byrne, Christopher D.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671046/
https://www.ncbi.nlm.nih.gov/pubmed/19208914
http://dx.doi.org/10.2337/db08-1688