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Munc18c Depletion Selectively Impairs the Sustained Phase of Insulin Release
OBJECTIVE: The Sec1/Munc18 protein Munc18c has been implicated in Syntaxin 4–mediated exocytosis events, although its purpose in exocytosis has remained elusive. Given that Syntaxin 4 functions in the second phase of glucose-stimulated insulin secretion (GSIS), we hypothesized that Munc18c would als...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Diabetes Association
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671048/ https://www.ncbi.nlm.nih.gov/pubmed/19188424 http://dx.doi.org/10.2337/db08-1059 |