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PPARγ Variant Influences Angiographic Outcome and 10-Year Cardiovascular Risk in Male Symptomatic Coronary Artery Disease Patients

OBJECTIVE: Activation of peroxisome proliferator–activated receptor (PPAR)-γ signaling influences metabolic profiles and the propensity toward inflammation. Small-molecule stimulation of PPARγ is investigated for secondary prevention of cardiovascular disease. The common PPARγ Pro12Ala variant has f...

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Detalles Bibliográficos
Autores principales: Regieli, Jakub J., Jukema, J. Wouter, Doevendans, Pieter A., Zwinderman, Aeilko H., van der Graaf, Yolanda, Kastelein, John J., Grobbee, Diederick E.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671091/
https://www.ncbi.nlm.nih.gov/pubmed/19228871
http://dx.doi.org/10.2337/dc08-1819