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Prediction of Protein Binding Regions in Disordered Proteins

Many disordered proteins function via binding to a structured partner and undergo a disorder-to-order transition. The coupled folding and binding can confer several functional advantages such as the precise control of binding specificity without increased affinity. Additionally, the inherent flexibi...

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Detalles Bibliográficos
Autores principales: Mészáros, Bálint, Simon, István, Dosztányi, Zsuzsanna
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671142/
https://www.ncbi.nlm.nih.gov/pubmed/19412530
http://dx.doi.org/10.1371/journal.pcbi.1000376