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A Conserved Multi-Gene Family Induces Cross-Reactive Antibodies Effective in Defense against Plasmodium falciparum

BACKGROUND: Two related merozoite surface proteins, MSP3 and MSP6, have previously been identified as targets of antibody-dependent cellular inhibition (ADCI), a protective mechanism against Plasmodium falciparum malaria. Both MSP3 and MSP6 share a common characteristic small N-terminal signature am...

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Detalles Bibliográficos
Autores principales: Singh, Subhash, Soe, Soe, Weisman, Simon, Barnwell, John W., Pérignon, Jean Louis, Druilhe, Pierre
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671155/
https://www.ncbi.nlm.nih.gov/pubmed/19404387
http://dx.doi.org/10.1371/journal.pone.0005410