Cargando…
A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation
Transcription factor (TF) regulation is often post-translational. TF modifications such as reversible phosphorylation and missense mutations, which can act independent of TF expression level, are overlooked by differential expression analysis. Using bovine Piedmontese myostatin mutants as proof-of-c...
Autores principales: | , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671163/ https://www.ncbi.nlm.nih.gov/pubmed/19412532 http://dx.doi.org/10.1371/journal.pcbi.1000382 |