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A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation
Transcription factor (TF) regulation is often post-translational. TF modifications such as reversible phosphorylation and missense mutations, which can act independent of TF expression level, are overlooked by differential expression analysis. Using bovine Piedmontese myostatin mutants as proof-of-c...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671163/ https://www.ncbi.nlm.nih.gov/pubmed/19412532 http://dx.doi.org/10.1371/journal.pcbi.1000382 |