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Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol

Betulinic Acid (BetA) and its derivatives have been extensively studied in the past for their anti-tumor effects, but relatively little is known about its precursor Betulin (BE). We found that BE induces apoptosis utilizing a similar mechanism as BetA and is prevented by cyclosporin A (CsA). BE indu...

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Detalles Bibliográficos
Autores principales: Mullauer, Franziska B., Kessler, Jan H., Medema, Jan Paul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671171/
https://www.ncbi.nlm.nih.gov/pubmed/19399186
http://dx.doi.org/10.1371/journal.pone.0005361