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Betulin Is a Potent Anti-Tumor Agent that Is Enhanced by Cholesterol
Betulinic Acid (BetA) and its derivatives have been extensively studied in the past for their anti-tumor effects, but relatively little is known about its precursor Betulin (BE). We found that BE induces apoptosis utilizing a similar mechanism as BetA and is prevented by cyclosporin A (CsA). BE indu...
Autores principales: | Mullauer, Franziska B., Kessler, Jan H., Medema, Jan Paul |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671171/ https://www.ncbi.nlm.nih.gov/pubmed/19399186 http://dx.doi.org/10.1371/journal.pone.0005361 |
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