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Using Triplet Periodicity of Nucleotide Sequences for Finding Potential Reading Frame Shifts in Genes

We introduce a novel approach for the detection of possible mutations leading to a reading frame (RF) shift in a gene. Deletions and insertions of DNA coding regions are considerable events for genes because an RF shift results in modifications of the extensive region of amino acid sequence coded by...

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Detalles Bibliográficos
Autores principales: Frenkel, F.E., Korotkov, E.V.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671204/
https://www.ncbi.nlm.nih.gov/pubmed/19261626
http://dx.doi.org/10.1093/dnares/dsp002