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Flotillins Interact with PSGL-1 in Neutrophils and, upon Stimulation, Rapidly Organize into Membrane Domains Subsequently Accumulating in the Uropod

BACKGROUND: Neutrophils polarize and migrate in response to chemokines. Different types of membrane microdomains (rafts) have been postulated to be present in rear and front of polarized leukocytes and disruption of rafts by cholesterol sequestration prevents leukocyte polarization. Reggie/flotillin...

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Detalles Bibliográficos
Autores principales: Rossy, Jérémie, Schlicht, Dominique, Engelhardt, Britta, Niggli, Verena
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671458/
https://www.ncbi.nlm.nih.gov/pubmed/19404397
http://dx.doi.org/10.1371/journal.pone.0005403