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KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay

BACKGROUND: Mutations in the KRAS gene are one of the most frequent genetic abnormalities in ovarian carcinoma. They are of renewed interest as new epidermal growth factor receptor (EGFR)-targeted therapies are being investigated for use in ovarian carcinoma. As KRAS mutations are associated with po...

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Detalles Bibliográficos
Autores principales: Auner, Veronika, Kriegshäuser, Gernot, Tong, Dan, Horvat, Reinhard, Reinthaller, Alexander, Mustea, Alexander, Zeillinger, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671522/
https://www.ncbi.nlm.nih.gov/pubmed/19358724
http://dx.doi.org/10.1186/1471-2407-9-111