Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis

Caspase-9 is the protease that mediates the intrinsic pathway of apoptosis, a type of cell death. Activation of caspase-9 is a multi-step process that requires dATP or ATP and involves at least two proteins, cytochrome c and Apaf-1. In this study, we mathematically model caspase-9 activation by usin...

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Detalles Bibliográficos
Autores principales: Ryu, Seongho, Lin, Shih-chieh, Ugel, Nadia, Antoniotti, Marco, Mishra, Bud
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671592/
https://www.ncbi.nlm.nih.gov/pubmed/19333786
http://dx.doi.org/10.1007/s11693-009-9022-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671592/
https://www.ncbi.nlm.nih.gov/pubmed/19333786
http://dx.doi.org/10.1007/s11693-009-9022-y

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