Cargando…
Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis
Caspase-9 is the protease that mediates the intrinsic pathway of apoptosis, a type of cell death. Activation of caspase-9 is a multi-step process that requires dATP or ATP and involves at least two proteins, cytochrome c and Apaf-1. In this study, we mathematically model caspase-9 activation by usin...
| Autores principales: | , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671592/ https://www.ncbi.nlm.nih.gov/pubmed/19333786 http://dx.doi.org/10.1007/s11693-009-9022-y |