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Rapid Influx and Death of Plasmacytoid Dendritic Cells in Lymph Nodes Mediate Depletion in Acute Simian Immunodeficiency Virus Infection

Plasmacytoid dendritic cells (pDC) are essential innate immune system cells that are lost from the circulation in human immunodeficiency virus (HIV)–infected individuals associated with CD4(+) T cell decline and disease progression. pDC depletion is thought to be caused by migration to tissues or ce...

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Detalles Bibliográficos
Autores principales: Brown, Kevin N., Wijewardana, Viskam, Liu, Xiangdong, Barratt-Boyes, Simon M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671605/
https://www.ncbi.nlm.nih.gov/pubmed/19424421
http://dx.doi.org/10.1371/journal.ppat.1000413