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HIV Evolution in Early Infection: Selection Pressures, Patterns of Insertion and Deletion, and the Impact of APOBEC

The pattern of viral diversification in newly infected individuals provides information about the host environment and immune responses typically experienced by the newly transmitted virus. For example, sites that tend to evolve rapidly across multiple early-infection patients could be involved in e...

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Detalles Bibliográficos
Autores principales: Wood, Natasha, Bhattacharya, Tanmoy, Keele, Brandon F., Giorgi, Elena, Liu, Michael, Gaschen, Brian, Daniels, Marcus, Ferrari, Guido, Haynes, Barton F., McMichael, Andrew, Shaw, George M., Hahn, Beatrice H., Korber, Bette, Seoighe, Cathal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671846/
https://www.ncbi.nlm.nih.gov/pubmed/19424423
http://dx.doi.org/10.1371/journal.ppat.1000414