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Pathologic Prion Protein Infects Cells by Lipid-Raft Dependent Macropinocytosis
Transmissible spongiform encephalopathies, including variant-Creutzfeldt-Jakob disease (vCJD) in humans and bovine spongiform encephalopathies in cattle, are fatal neurodegenerative disorders characterized by protein misfolding of the host cellular prion protein (PrP(C)) to the infectious scrapie fo...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671965/ https://www.ncbi.nlm.nih.gov/pubmed/19390657 http://dx.doi.org/10.1371/journal.pone.0003314 |