Pathologic Prion Protein Infects Cells by Lipid-Raft Dependent Macropinocytosis

Transmissible spongiform encephalopathies, including variant-Creutzfeldt-Jakob disease (vCJD) in humans and bovine spongiform encephalopathies in cattle, are fatal neurodegenerative disorders characterized by protein misfolding of the host cellular prion protein (PrP(C)) to the infectious scrapie fo...

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Detalles Bibliográficos
Autores principales: Wadia, Jehangir S., Schaller, Monica, Williamson, R. Anthony, Dowdy, Steven F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671965/
https://www.ncbi.nlm.nih.gov/pubmed/19390657
http://dx.doi.org/10.1371/journal.pone.0003314

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