High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors

BACKGROUND: Morphine and its derivatives are key drugs in pain control. Despite its well-known analgesic properties morphine at high concentrations may be proalgesic. Particularly, short-lasting painful sensations have been reported upon dermal application of morphine. To study a possible involvemen...

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Detalles Bibliográficos
Autores principales: Forster, Alexander B, Reeh, Peter W, Messlinger, Karl, Fischer, Michael JM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672059/
https://www.ncbi.nlm.nih.gov/pubmed/19371406
http://dx.doi.org/10.1186/1744-8069-5-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672059/
https://www.ncbi.nlm.nih.gov/pubmed/19371406
http://dx.doi.org/10.1186/1744-8069-5-17

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