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Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes
Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is associated with a downregulation of the pattern recognition receptors Toll-like receptor (TL...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672063/ https://www.ncbi.nlm.nih.gov/pubmed/19371402 http://dx.doi.org/10.1186/1746-1596-4-12 |