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DNA sequence and structural properties as predictors of human and mouse promoters

Promoters play a central role in gene regulation, yet our power to discriminate them from non-promoter sequences in higher eukaryotes is mainly restricted to those associated with CpG islands. Here, we examined in silico the promoters of 30,954 human and 18,083 mouse transcripts in the DBTSS databas...

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Detalles Bibliográficos
Autores principales: Akan, Pelin, Deloukas, Panos
Formato: Texto
Lenguaje:English
Publicado: Elsevier/North-Holland 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672154/
https://www.ncbi.nlm.nih.gov/pubmed/18234453
http://dx.doi.org/10.1016/j.gene.2007.12.011