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Silencing Inhibits Cre-Mediated Recombination of the Z/AP and Z/EG Reporters in Adult Cells

BACKGROUND: The Cre-loxP system has been used to enable tissue specific activation, inactivation and mutation of many genes in vivo and has thereby greatly facilitated the genetic dissection of several cellular and developmental processes. In such studies, Cre-reporter strains, which carry a Cre-act...

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Detalles Bibliográficos
Autores principales: Long, Michael A., Rossi, Fabio M. V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672169/
https://www.ncbi.nlm.nih.gov/pubmed/19415111
http://dx.doi.org/10.1371/journal.pone.0005435