CD98hc facilitates B cell proliferation and adaptive humoral immunity

Proliferation of antigen-specific lymphocytes and resulting clonal expansion is essential for adaptive immunity. We report that B cell-specific deletion of CD98hc reduced antibody responses due to total suppression of B cell proliferation and subsequent plasma cell formation. Deletion of CD98hc didn...

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Detalles Bibliográficos
Autores principales: Cantor, Joseph, Browne, Cecille D., Ruppert, Raphael, Féral, Chloé C., Fässler, Reinhard, Rickert, Robert C., Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672195/
https://www.ncbi.nlm.nih.gov/pubmed/19270713
http://dx.doi.org/10.1038/ni.1712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672195/
https://www.ncbi.nlm.nih.gov/pubmed/19270713
http://dx.doi.org/10.1038/ni.1712

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