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Review of tenecteplase (TNKase) in the treatment of acute myocardial infarction

TNKase is a genetically engineered variant of the alteplase molecule. Three different mutations result in an increase of the plasma half-life, of the resistance to plasminogen-activator inhibitor 1 and of the thrombolytic potency against platelet-rich thrombi. Among available agents in clinical prac...

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Detalles Bibliográficos
Autores principales: Melandri, Giovanni, Vagnarelli, Fabio, Calabrese, Daniela, Semprini, Franco, Nanni, Samuele, Branzi, Angelo
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672445/
https://www.ncbi.nlm.nih.gov/pubmed/19436656