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Tubulin Tyrosination Is Required for the Proper Organization and Pathfinding of the Growth Cone

BACKGROUND: During development, neuronal growth cones integrate diffusible and contact guidance cues that are conveyed to both actin and microtubule (MT) cytoskeletons and ensure axon outgrowth and pathfinding. Although several post-translational modifications of tubulin have been identified and des...

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Detalles Bibliográficos
Autores principales: Marcos, Séverine, Moreau, Julie, Backer, Stéphanie, Job, Didier, Andrieux, Annie, Bloch-Gallego, Evelyne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672595/
https://www.ncbi.nlm.nih.gov/pubmed/19404406
http://dx.doi.org/10.1371/journal.pone.0005405