Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

Ryanodine receptor type 1 (RyR1) produces spatially and temporally defined Ca(2+) signals in several cell types. How signals received in the cytoplasmic domain are transmitted to the ion gate and how the channel gates are unknown. We used EGTA or neuroactive PCB 95 to stabilize the full closed or op...

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Detalles Bibliográficos
Autores principales: Samsó, Montserrat, Feng, Wei, Pessah, Isaac N, Allen, P. D
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672603/
https://www.ncbi.nlm.nih.gov/pubmed/19402748
http://dx.doi.org/10.1371/journal.pbio.1000085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672603/
https://www.ncbi.nlm.nih.gov/pubmed/19402748
http://dx.doi.org/10.1371/journal.pbio.1000085

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