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Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating
Ryanodine receptor type 1 (RyR1) produces spatially and temporally defined Ca(2+) signals in several cell types. How signals received in the cytoplasmic domain are transmitted to the ion gate and how the channel gates are unknown. We used EGTA or neuroactive PCB 95 to stabilize the full closed or op...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672603/ https://www.ncbi.nlm.nih.gov/pubmed/19402748 http://dx.doi.org/10.1371/journal.pbio.1000085 |