Reawakening Retrocyclins: Ancestral Human Defensins Active Against HIV-1

Human alpha and beta defensins contribute substantially to innate immune defenses against microbial and viral infections. Certain nonhuman primates also produce theta-defensins—18 residue cyclic peptides that act as HIV-1 entry inhibitors. Multiple human theta-defensin genes exist, but they harbor a...

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Detalles Bibliográficos
Autores principales: Venkataraman, Nitya, Cole, Amy L, Ruchala, Piotr, Waring, Alan J, Lehrer, Robert I, Stuchlik, Olga, Pohl, Jan, Cole, Alexander M
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672613/
https://www.ncbi.nlm.nih.gov/pubmed/19402752
http://dx.doi.org/10.1371/journal.pbio.1000095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672613/
https://www.ncbi.nlm.nih.gov/pubmed/19402752
http://dx.doi.org/10.1371/journal.pbio.1000095

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