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Reawakening Retrocyclins: Ancestral Human Defensins Active Against HIV-1
Human alpha and beta defensins contribute substantially to innate immune defenses against microbial and viral infections. Certain nonhuman primates also produce theta-defensins—18 residue cyclic peptides that act as HIV-1 entry inhibitors. Multiple human theta-defensin genes exist, but they harbor a...
Autores principales: | Venkataraman, Nitya, Cole, Amy L, Ruchala, Piotr, Waring, Alan J, Lehrer, Robert I, Stuchlik, Olga, Pohl, Jan, Cole, Alexander M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672613/ https://www.ncbi.nlm.nih.gov/pubmed/19402752 http://dx.doi.org/10.1371/journal.pbio.1000095 |
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