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Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

The engulfment of apoptotic cells is required for normal metazoan development and tissue remodeling. In Caenorhabditis elegans, two parallel and partially redundant conserved pathways act in cell-corpse engulfment. One pathway includes the adaptor protein CED-2 CrkII and the small GTPase CED-10 Rac,...

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Detalles Bibliográficos
Autores principales: Hurwitz, Michael E, Vanderzalm, Pamela J, Bloom, Laird, Goldman, Julia, Garriga, Gian, Horvitz, H. Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672617/
https://www.ncbi.nlm.nih.gov/pubmed/19402756
http://dx.doi.org/10.1371/journal.pbio.1000099