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Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarization

BACKGROUND: Recognition of pathogens by dendritic cells (DCs) through interaction with pattern recognition receptors, including Toll like receptors (TLR), is crucial for the initiation of appropriate polarized T helper (Th) cell responses. Yet, the characteristics and differences in molecular profil...

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Detalles Bibliográficos
Autores principales: van Riet, Elly, Everts, Bart, Retra, Kim, Phylipsen, Marion, van Hellemond, Jaap J, Tielens, Aloysius GM, van der Kleij, Desiree, Hartgers, Franca C, Yazdanbakhsh, Maria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672924/
https://www.ncbi.nlm.nih.gov/pubmed/19193240
http://dx.doi.org/10.1186/1471-2172-10-9