Structural changes in the cytoplasmic pore of the Kir1.1 channel during pH(i)-gating probed by FRET

Kir1.1 channels are important in maintaining K(+ )homeostasis in the kidney. Intracellular acidification reversibly closes the Kir1.1 channel and thus decreases K(+ )secretion. In this study, we used Foster resonance energy transfer (FRET) to determine whether the conformation of the cytoplasmic por...

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Detalles Bibliográficos
Autores principales: Lee, Jay-Ron, Shieh, Ru-Chi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672938/
https://www.ncbi.nlm.nih.gov/pubmed/19272129
http://dx.doi.org/10.1186/1423-0127-16-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672938/
https://www.ncbi.nlm.nih.gov/pubmed/19272129
http://dx.doi.org/10.1186/1423-0127-16-29

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