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Structural changes in the cytoplasmic pore of the Kir1.1 channel during pH(i)-gating probed by FRET
Kir1.1 channels are important in maintaining K(+ )homeostasis in the kidney. Intracellular acidification reversibly closes the Kir1.1 channel and thus decreases K(+ )secretion. In this study, we used Foster resonance energy transfer (FRET) to determine whether the conformation of the cytoplasmic por...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672938/ https://www.ncbi.nlm.nih.gov/pubmed/19272129 http://dx.doi.org/10.1186/1423-0127-16-29 |