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The N-terminal domain of Escherichia coli RecA have multiple functions in promoting homologous recombination

Escherichia coli RecA mediates homologous recombination, a process essential to maintaining genome integrity. In the presence of ATP, RecA proteins bind a single-stranded DNA (ssDNA) to form a RecA-ssDNA presynaptic nucleoprotein filament that captures donor double-stranded DNA (dsDNA), searches for...

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Detalles Bibliográficos
Autores principales: Lee, Chien-Der, Wang, Ting-Fang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672939/
https://www.ncbi.nlm.nih.gov/pubmed/19338667
http://dx.doi.org/10.1186/1423-0127-16-37