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Construction and analysis of a modular model of caspase activation in apoptosis

BACKGROUND: A key physiological mechanism employed by multicellular organisms is apoptosis, or programmed cell death. Apoptosis is triggered by the activation of caspases in response to both extracellular (extrinsic) and intracellular (intrinsic) signals. The extrinsic and intrinsic pathways are cha...

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Detalles Bibliográficos
Autores principales: Harrington, Heather A, Ho, Kenneth L, Ghosh, Samik, Tung, KC
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672941/
https://www.ncbi.nlm.nih.gov/pubmed/19077196
http://dx.doi.org/10.1186/1742-4682-5-26