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Construction and analysis of a modular model of caspase activation in apoptosis
BACKGROUND: A key physiological mechanism employed by multicellular organisms is apoptosis, or programmed cell death. Apoptosis is triggered by the activation of caspases in response to both extracellular (extrinsic) and intracellular (intrinsic) signals. The extrinsic and intrinsic pathways are cha...
Autores principales: | Harrington, Heather A, Ho, Kenneth L, Ghosh, Samik, Tung, KC |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672941/ https://www.ncbi.nlm.nih.gov/pubmed/19077196 http://dx.doi.org/10.1186/1742-4682-5-26 |
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