A Complex Extracellular Sphingomyelinase of Pseudomonas aeruginosa Inhibits Angiogenesis by Selective Cytotoxicity to Endothelial Cells

The hemolytic phospholipase C (PlcHR) expressed by Pseudomonas aeruginosa is the original member of a Phosphoesterase Superfamily, which includes phosphorylcholine-specific phospholipases C (PC-PLC) produced by frank and opportunistic pathogens. PlcHR, but not all its family members, is also a poten...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasil, Michael L., Stonehouse, Martin J., Vasil, Adriana I., Wadsworth, Sandra J., Goldfine, Howard, Bolcome, Robert E., Chan, Joanne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673038/
https://www.ncbi.nlm.nih.gov/pubmed/19424430
http://dx.doi.org/10.1371/journal.ppat.1000420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673038/
https://www.ncbi.nlm.nih.gov/pubmed/19424430
http://dx.doi.org/10.1371/journal.ppat.1000420

Ejemplares similares