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DEAR1 Is a Dominant Regulator of Acinar Morphogenesis and an Independent Predictor of Local Recurrence-Free Survival in Early-Onset Breast Cancer

BACKGROUND: Breast cancer in young women tends to have a natural history of aggressive disease for which rates of recurrence are higher than in breast cancers detected later in life. Little is known about the genetic pathways that underlie early-onset breast cancer. Here we report the discovery of D...

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Detalles Bibliográficos
Autores principales: Lott, Steven T., Chen, Nanyue, Chandler, Dawn S., Yang, Qifeng, Wang, Luo, Rodriguez, Marivonne, Xie, Hongyan, Balasenthil, Seetharaman, Buchholz, Thomas A., Sahin, Aysegul A., Chaung, Katrina, Zhang, Baili, Olufemi, Shodimu-Emmanu, Chen, Jinyun, Adams, Henry, Band, Vimla, El-Naggar, Adel K., Frazier, Marsha L., Keyomarsi, Khandan, Hunt, Kelly K., Sen, Subrata, Haffty, Bruce, Hewitt, Stephen M., Krahe, Ralf, Killary, Ann McNeill
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673042/
https://www.ncbi.nlm.nih.gov/pubmed/19536326
http://dx.doi.org/10.1371/journal.pmed.1000068