The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in these processes is still poorly understood. Here, we provide evidence for a new Pif1 function by demonstrating that its absence promotes genetic instability of alleles of...

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Detalles Bibliográficos
Autores principales: Ribeyre, Cyril, Lopes, Judith, Boulé, Jean-Baptiste, Piazza, Aurèle, Guédin, Aurore, Zakian, Virginia A., Mergny, Jean-Louis, Nicolas, Alain
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673046/
https://www.ncbi.nlm.nih.gov/pubmed/19424434
http://dx.doi.org/10.1371/journal.pgen.1000475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673046/
https://www.ncbi.nlm.nih.gov/pubmed/19424434
http://dx.doi.org/10.1371/journal.pgen.1000475

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