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Evaluation of anti-IL-6 monoclonal antibody therapy using murine type II collagen-induced arthritis

Interleukin-6 is a multifunctional cytokine that is critical for T/B-cell differentiation and maturation, immunoglobulin secretion, acute-phase protein production, and macrophage/monocyte functions. Extensive research into the biology of IL-6 has implicated IL-6 in the pathophysiology and pathogenes...

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Detalles Bibliográficos
Autores principales: Liang, Bailin, Song, Zheng, Wu, Bin, Gardner, Debra, Shealy, David, Song, Xiao-Yu, Wooley, Paul H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673212/
https://www.ncbi.nlm.nih.gov/pubmed/19368720
http://dx.doi.org/10.1186/1476-9255-6-10