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The Human Oxidative DNA Glycosylase NEIL1 Excises Psoralen-induced Interstrand DNA Cross-links in a Three-stranded DNA Structure

Previously, we have demonstrated that human oxidative DNA glycosylase NEIL1 excises photoactivated psoralen-induced monoadducts but not genuine interstrand cross-links (ICLs) in duplex DNA. It has been postulated that the repair of ICLs in mammalian cells is mainly linked to DNA replication and proc...

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Detalles Bibliográficos
Autores principales: Couvé, Sophie, Macé-Aimé, Gaëtane, Rosselli, Filippo, Saparbaev, Murat K.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673265/
https://www.ncbi.nlm.nih.gov/pubmed/19258314
http://dx.doi.org/10.1074/jbc.M900746200