Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands

Many restriction endonucleases are dimers that act symmetrically at palindromic DNA sequences, with each active site cutting one strand. In contrast, FokI acts asymmetrically at a non-palindromic sequence, cutting ‘top’ and ‘bottom’ strands 9 and 13 nucleotides downstream of the site. FokI is a mono...

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Detalles Bibliográficos
Autores principales: Sanders, Kelly L., Catto, Lucy E., Bellamy, Stuart R. W., Halford, Stephen E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673415/
https://www.ncbi.nlm.nih.gov/pubmed/19223323
http://dx.doi.org/10.1093/nar/gkp046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673415/
https://www.ncbi.nlm.nih.gov/pubmed/19223323
http://dx.doi.org/10.1093/nar/gkp046

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