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HMGB1 and HMGB2 proteins up-regulate cellular expression of human topoisomerase IIα

Topoisomerase IIα (topo IIα) is a nuclear enzyme involved in several critical processes, including chromosome replication, segregation and recombination. Previously we have shown that chromosomal protein HMGB1 interacts with topo IIα, and stimulates its catalytic activity. Here we show the effect of...

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Detalles Bibliográficos
Autores principales: Štros, Michal, Polanská, Eva, Štruncová, Soňa, Pospíšilová, Šárka
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673423/
https://www.ncbi.nlm.nih.gov/pubmed/19223331
http://dx.doi.org/10.1093/nar/gkp067