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Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

The ability to rapidly and efficiently generate reliable Cre/loxP conditional transgenic mice would greatly complement global high-throughput gene targeting initiatives aimed at identifying gene function in the mouse. We report here the generation of Cre/loxP conditional ROSA26-targeted ES cells wit...

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Detalles Bibliográficos
Autores principales: Nyabi, Omar, Naessens, Michael, Haigh, Katharina, Gembarska, Agnieszka, Goossens, Steven, Maetens, Marion, De Clercq, Sarah, Drogat, Benjamin, Haenebalcke, Lieven, Bartunkova, Sonia, De Vos, Ilse, De Craene, Bram, Karimi, Mansour, Berx, Geert, Nagy, Andras, Hilson, Pierre, Marine, Jean-Christophe, Haigh, Jody J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673446/
https://www.ncbi.nlm.nih.gov/pubmed/19279185
http://dx.doi.org/10.1093/nar/gkp112