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A Population-Based Clinical Trial of Irinotecan and Carboplatin

Purpose. Phase I trials of anticancer drugs are commonly conducted using the method of modified Fibonacci. We have developed a population-based design for phase I trials of combining anticancer drugs such as irinotecan and carboplatin. Patients and Methods. Intrapatient dose escalation of irinotecan...

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Detalles Bibliográficos
Autores principales: Lau, Derick, Huynh, Minh, Johl, Jewel
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673471/
https://www.ncbi.nlm.nih.gov/pubmed/19404408
http://dx.doi.org/10.1155/2009/458528