MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR-γ Agonist Lowers Triglyceride Independently of PPAR-α Activation

MBX-102/JNJ-39659100 (MBX-102) is a selective, partial PPAR-γ agonist that lowers glucose in the absence of some of the side effects, such as weight gain and edema, that are observed with the TZDs. Interestingly MBX-102 also displays pronounced triglyceride lowering in preclinical rodent models and...

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Detalles Bibliográficos
Autores principales: Chandalia, Apurva, Clarke, Holly J., Clemens, L. Edward, Pandey, Bindu, Vicena, Vic, Lee, Paul, Lavan, Brian E., Gregoire, Francine M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673481/
https://www.ncbi.nlm.nih.gov/pubmed/19404482
http://dx.doi.org/10.1155/2009/706852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673481/
https://www.ncbi.nlm.nih.gov/pubmed/19404482
http://dx.doi.org/10.1155/2009/706852

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