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Mutation of the Protein Kinase C Site in Borna Disease Virus Phosphoprotein Abrogates Viral Interference with Neuronal Signaling and Restores Normal Synaptic Activity

Understanding the pathogenesis of infection by neurotropic viruses represents a major challenge and may improve our knowledge of many human neurological diseases for which viruses are thought to play a role. Borna disease virus (BDV) represents an attractive model system to analyze the molecular mec...

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Detalles Bibliográficos
Autores principales: Prat, Christine M. A., Schmid, Sonja, Farrugia, Fanny, Cenac, Nicolas, Le Masson, Gwendal, Schwemmle, Martin, Gonzalez-Dunia, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673689/
https://www.ncbi.nlm.nih.gov/pubmed/19424436
http://dx.doi.org/10.1371/journal.ppat.1000425