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Identification of an Intracellular Site of Prion Conversion

Prion diseases are fatal, neurodegenerative disorders in humans and animals and are characterized by the accumulation of an abnormally folded isoform of the cellular prion protein (PrP(C)), denoted PrP(Sc), which represents the major component of infectious scrapie prions. Characterization of the me...

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Detalles Bibliográficos
Autores principales: Marijanovic, Zrinka, Caputo, Anna, Campana, Vincenza, Zurzolo, Chiara
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673690/
https://www.ncbi.nlm.nih.gov/pubmed/19424437
http://dx.doi.org/10.1371/journal.ppat.1000426